The ipsilesional arm of stroke patients often has functionally limiting deficits in motor control and dexterity that depend on the side of the brain that is lesioned and that increase with the severity of paretic arm impairment. However, remediation of the ipsilesional arm has yet to be integrated into the usual standard of care for upper limb rehabilitation in stroke, largely due to a lack of translational research examining the effects of ipsilesional-arm intervention. We now ask whether ipsilesional-arm training, tailored (...) to the hemisphere-specific nature of ipsilesional-arm motor deficits in participants with moderate to severe contralesional paresis, improves ipsilesional arm performance and generalizes to improve functional independence. We assessed the effects of this intervention on ipsilesional arm unilateral performance [Jebsen–Taylor Hand Function Test ], ipsilesional grip strength, contralesional arm impairment level [Fugl–Meyer Assessment ], and functional independence [Functional independence measure ]. Intervention occurred over a 3 week period for 1.5 h/session, three times each week. All sessions included virtual reality tasks that targeted the specific motor control deficits associated with either left or right hemisphere damage, followed by graded dexterity training in real-world tasks. We also exposed participants to 3 weeks of sham training to control for the non-specific effects of therapy visits and interactions. We conducted five test-sessions: two pre-tests and three post-tests. Our results indicate substantial improvements in the less-impaired arm performance, without detriment to the paretic arm that transferred to improved functional independence in all three posttests, indicating durability of training effects for at least 3 weeks. We provide evidence for establishing the basis of a rehabilitation approach that includes evaluation and remediation of the ipsilesional arm in moderately to severely impaired stroke survivors. This study was originally a crossover design; however, we were unable to complete the second arm of the study due to the COVID-19 pandemic. We report the results from the first arm of the planned design as a longitudinal study. (shrink)

Many prescriptions offered in the literature for enhancing creativity and innovation in organizations raise ethical concerns, yet creativity researchers rarely discuss ethics. We identify four categories of behavior proffered as a means for fostering creativity that raise serious ethical issues: breaking rules and standard operating procedures; challenging authority and avoiding tradition; creating conflict, competition and stress; and taking risks. We discuss each category, briefly identifying research supporting these prescriptions for fostering creativity and then we delve into ethical issues associated with (...) engaging in the prescribed behavior. These four rubrics illustrate ethical issues that need to be incorporated into the creativity and innovation literature. Recommendations for how organizations can respond to the ethical issues are offered based on practices of exemplary organizations and theories of organizational ethics. A research agenda for empirically investigating the ethical impact these four categories of behavior have on organizations concludes the article. (shrink)

Osteoporosis (OP) is a bone disease which affects a number of post‐menopausal females and puts many at risk for fractures. A large number of patients are taking bisphosphonates (BPs) to treat their OP and a rare complication is the development of atypical femoral fractures (AFF). No real explanations for the mechanisms underlying the basis for development of where AFF develop while on BPs has emerged. The present hypothesis will discuss the possibility that part of the risk for an AFF is (...) a secondary effect of BPs on a subset of vascular cells in a genetically at‐risk population, leading to localized deregulation of the endothelial cell (EC)‐bone cell‐matrix units in nutrient channels/canals of the femur and increased risk for AFF. This concept of targeting ECs is consistent with location of AFF in the femur, the bilateral risk for occurrence of AFF, and the requirement for long term exposure to the drugs. (shrink)

There was a strong consensus in the commentaries that animals' performances in metacognition paradigms indicate high-level decisional processes that cannot be explained associatively. Our response summarizes this consensus and the support for the idea that these performances demonstrate animal metacognition. We amplify the idea that there is an adaptive advantage favoring animals who can – in an immediate moment of difficulty or uncertainty – construct a decisional assemblage that lets them find an appropriate behavioral solution. A working consciousness would serve (...) this function well. This explains why animals may have the functional equivalent of human declarative consciousness. However, like other commentators who were friendly to this equivalence, we approach carefully the stronger claims that animals' metacognitive performances imply full-blown self-awareness or phenomenal consciousness. We discuss the commentators' interesting ideas for future research, as well as their intriguing ideas about the evolution and development of metacognition and its relation to theory of mind. We also discuss residual confusions about existing research and remaining methodological issues. (shrink)

There is a growing interest in assessing how cognitive processes fluidly adjust across trials within a task. Dynamic adjustments of control are typically measured using the congruency sequence effect (CSE), which refers to the reduction in interference following an incongruent trial, relative to a congruent trial. However, it is unclear if this effect stems from a general control mechanism or a distinct process tied to cross-trial reengagement of the task set. We examine the relationship of the CSE with another measure (...) of control referred to as the item-specific proportion congruency effect (ISPC), the finding that frequently occurring congruent items exhibit greater interference than items that are often incongruent. If the two effects reflect the same control mechanism, one should find interactive effects of CSE and ISPC. We report results from three experiments utilizing a vocal Stroop task that manipulated these two effects while controlling for variables that are often confounded in the literature. Across three experiments, we observed large CSE and ISPC effects. Importantly, these effects were robustly additive with one another (Bayes Factor for the null approaching 9). This finding indicates that the CSE and ISPC arise from independent mechanisms and suggests the CSE in Stroop may reflect a more general response adjustment process that is not directly tied to trial-by-trial changes in attentional control. (shrink)

In his autobiographical-biographical study, Father and Son, Edmund Gosse describes how one evening, during his childhood, while his father was praying at - or, rather, over - his bed, a rather large insect dark and flat, with more legs than a self-respecting insect ought to need, appeared at the bottom of the counterpane, and slowly advanced… I bore it in silent fascination till it almost tickled my chin, and then I screamed ‘Papa! Papa!’. My Father rose in great dudgeon, removed (...) the insect and then gave me a tremendous lecture. 1. (shrink)

Poverty, inequality, violence, environmental degradation, and tyranny continue to afflict the world. Ethics of Global Development offers a moral reflection on the ends and means of local, national, and global efforts to overcome these five scourges. After emphasizing the role of ethics in development studies, policy-making, and practice, David A. Crocker analyzes and evaluates Amartya Sen's philosophy of development in relation to alternative ethical outlooks. He argues that Sen's turn to robust ideals of human agency and democracy improves on (...) both Sen's earlier emphasis on 'capabilities and functionings' and Martha Nussbaum's version of the capability orientation. This agency-focused capability approach is then extended and strengthened by applying it to the challenges of consumerism and hunger, the development responsibilities of affluent individuals and nations, and the dilemmas of globalization. Throughout the book the author argues for the importance of more inclusive and deliberative democratic institutions. (shrink)

Although the basic ideas of the ontological argument can be found in Aristotle and Philo Judaeus, the argument received its classical formulation in Anselm's Proslogion and his Reply to the objections raised by Gaunilo. During the succeeding nine centuries the argument has had a chequered career. It was supported by some scholastic theologians but rejected by Aquinas. Descartes and Leibniz offered their own versions of the proof but Kant's refutation of the argument has generally been accepted as conclusive during the (...) past century and a half. Nevertheless, interest in the proof has never completely disappeared—perhaps provoked by Aquinas' suggestion that the proof may be valid for God even though it cannot be valid for us because of the inadequacy of our knowledge of God. Recently there has been a revival of interest in the ontological argument. J. N. Findlay put the argument into reverse to show the necessary non-existence of God in an article in 1948 but in later writings he has suggested that the argument may have positive significance. In 1960 Norman Malcolm published a paper in which he distinguished two basically different forms of the ontological argument in the Proslogion and defended the possible validity of the second of them. (shrink)

Ethical reflection on the practice of war stands in a long tradition in Western philosophy and theology, a tradition which begins with the writings of Plato and Augustine and encompasses accounts of justified warfare offered by writers from the Medieval period to the present. Ethical reflection on nuclear war is of necessity a more recent theme. The past few years have seen an enormous increase in popular as well as scholarly concern with nuclear issues, and philosophers have joined theologians in (...) exploring the moral issues surrounding the harnessing of atomic forces in the service of war. (shrink)

On the evolution of mind Harry J. Jerison Most of us think of mind as a little person in the head, the 'knower' of reality (cf. Attneave,). ...

At the center of Rawls’s work post-1980 is the question of how legitimate coercive state action is possible in a liberal democracy under conditions of reasonable disagreement. And at the heart of Rawls’s answer to this question is his liberal principle of legitimacy. In this paper I argue that once we attend carefully to the depth and range of reasonable disagreement, Rawls’s liberal principle of legitimacy turns out to be either wildly utopian or simply toothless, depending on how one reads (...) the ideal of reciprocity it is meant to embody. To remedy this defect in Rawls’s theory, I␣undertake to develop the outlines of a democratic conception of legitimacy, drawing first on Rawls’s generic conception of legitimacy in The Law of Peoples and second on a revised understanding of reciprocity between free and equal citizens. On this revised understanding, what free and equal citizens owe one another is not reciprocity in judgment, but reciprocity of interests. (shrink)

ABSTRACT This essay tells the story of Perelman and Olbrechts-Tyteca's “dissociation of concepts,” which they introduced in 1958 and is in use as a tool of criticism by many rhetorical critics. The story begins in England with John Locke's development of associative reasoning in 1770 and then moves to France, with Remy de Gourmont extending associative reasoning with the concept of dissociation in 1899. Gourmont's dissociation crosses the Atlantic and is then developed by Kenneth Burke in 1931. In turn, Perelman (...) and Olbrechts-Tyteca absorbed and expanded Locke, Gourmont, and Burke's theories of association and dissociation in 1958. They crafted a tool, the dissociation of concepts, that equips rhetorical reasoning with the capacity to navigate between the promise and perils of fission and fusion. Since 1958, many scholars have made productive use of Perelman and Olbrechts-Tyteca's innovation. The essay concludes with some possible futures for their dissociation of concepts. (shrink)

In this clear and reasoned discussion of self- knowledge and the self, the author asks whether it is really possible to know ourselves as we really are. He illuminates issues about the nature of self-identity which are of fundamental importance in moral psychology, epistemology and literary criticism. Jopling focuses on the accounts of Stuart Hampshire, Jean-Paul Sartre and Richard Rorty, and dialogical philosophical psychology and illustrates his argument with examples from literature, drama and psychology.

This article investigates the claims made in the dedicatory epistle to Girolamo Manfredi’s De homine to have effected an Italian translation of various earlier works. First published in 1474, the De homine is strongly dependent on the pseudo-Aristotelian Problems, for which several translations into Latin were available by Manfredi’s time as well as the highly influential commentary by Pietro d’Abano. Focusing on one particular section of the De homine, on voice, this article offers an analysis of the various sources used (...) and of the extent to which Manfredi is indeed offering a translation or something different. This study concludes that Manfredi closely followed the translation by Bartolomeo da Messina and the commentary by Pietro d’Abano; it finds no clear evidence of his use of the translations by George of Trebizond or Theodore Gaza. Other sources used include especially Rhazes’ Ad Almansorem. (shrink)

Traditional explanations of multistable visual phenomena (e.g. ambiguous figures, perceptual rivalry) suggest that the basis for spontaneous reversals in perception lies in antagonistic connectivity within the visual system. In this review, we suggest an alternative, albeit speculative, explanation for visual multistability – that spontaneous alternations reflect responses to active, programmed events initiated by brain areas that integrate sensory and non-sensory information to coordinate a diversity of behaviors. Much evidence suggests that perceptual reversals are themselves more closely related to the expression (...) of a behavior than to passive sensory responses: (1) they are initiated spontaneously, often voluntarily, and are influenced by subjective variables such as attention and mood; (2) the alternation process is greatly facilitated with practice and compromised by lesions in non-visual cortical areas; (3) the alternation process has temporal dynamics similar to those of spontaneously initiated behaviors; (4) functional imaging reveals that brain areas associated with a variety of cognitive behaviors are specifically activated when vision becomes unstable. In this scheme, reorganizations of activity throughout the visual cortex, concurrent with perceptual reversals, are initiated by higher, largely non-sensory brain centers. Such direct intervention in the processing of the sensory input by brain structures associated with planning and motor programming might serve an important role in perceptual organization, particularly in aspects related to selective attention. (shrink)

We propose in this paper to focus upon the de-ontological self concept discoverable in Eastern and Western philosophical traditions. In a larger study, we intend to contrast this “no self” paradigm with major pro-ontological formulations of the self concept. These pro-ontological definitions can be divided into three basic types, namely the absolute-universal self, the transcendental-constituting self, and the natural-organic self.

Shepard has challenged psychologists to identify nonarbitrary principles of mind upon which to build a more explanatory and general cognitive science. I suggest that such nonarbitrary principles may fruitfully be sought not only in the laws of physics and mathematics, but also in the logical entailments of different categories of representation. In the example offered here, conceptualizing mental events as indexical with respect to the events they represent enables one to account parsimoniously for a wide range of empirical psychological phenomena. (...) [Shepard]. (shrink)

In Globalization and Justice, Kai Nielsen brings his distinctive and passionate voice and considerable philosophical abilities to one of the pressing issues of our time: Is justice possible in our increasingly globalized world? Nielsen argues that it is, though the demands of justice are great, the challenges substantial, and the odds very long. Without a clear philosophical understanding of justice and a firm and focused political will, Nielsen maintains, we are likely to have globalization without justice. This is surely correct.

In this remarkable study, David A. J. Richards combines an interpretive history of culture and law, political philosophy, and constitutional analysis to explain the background, development, and growing impact of two of the most important and challenging human rights movements of our time, feminism and gay rights. Richards argues that both movements are extensions of rights-based dissent, rooted in antebellum abolitionist feminism that condemned both American racism and sexism. He sees the progressive role of such radical dissent as an (...) emancipated moral voice in the American constitutional tradition. He examines the role of dissident African Americans, Jews, women, and homosexuals in forging alternative visions of rights-based democracy. He also draws special attention to Walt Whitman's visionary poetry, showing how it made space for the silenced and subjugated voices of homosexuals in public and private culture. According to Richards, contemporary feminism rediscovers and elaborates this earlier tradition. And, similarly, the movement for gay rights builds upon an interpretation of abolitionist feminism developed by Whitman in his defense, both in poetry and prose, of love between men. Richards explores Whitman's impact on pro-gay advocates, including John Addington Symonds, Havelock Ellis, Edward Carpenter, Oscar Wilde, and André Gide. He also discusses other diverse writers and reformers such as Margaret Sanger, Franz Boas, Elizabeth Stanton, W. E. B. DuBois, and Adrienne Rich. Richards addresses current controversies such as the exclusion of homosexuals from the military and from the right to marriage and concludes with a powerful defense of the struggle for such constitutional rights in terms of the principles of rights-based feminism. (shrink)

Understanding how activity in the brain leads to a subjective percept is of great interest to philosophers and neuroscientists alike. In the last years, neurophysiological experiments have approached this problem directly by measuring neural signals in animals as they experience well-defined visual percepts. Stimuli in these studies are often inherently ambiguous, and thus rely upon the subjective report, generally from trained monkeys, to provide a measure of perception. By correlating activity levels in the brain to this report, one can speculate (...) on the role of individual neurons and groups of neurons in the formation and maintenance of a particular percept. However, in order to draw valid conclusions from such experiments, it is critical that the responses accurately and reliably reflect what is perceived. For this reason, a number of behavioural paradigms have been developed to control and evaluate the truthfulness of responses from behaving animals. Here we describe several approaches to optimizing the reliability of a monkey's perceptual report, and argue that their combination provides an invaluable approach in the study of subjective visual perception. (shrink)

We propose a way in which Barsalou could strengthen his position and at the same time make a considerable dent in the category/abstraction problem (that he suggests remains unsolved). There exists a class of connectionist models that solves this problem parsimoniously and provides a mechanistic underpinning for the promising high-level architecture he proposes.

There is no agreement about the supplement at the end of the first line. almost certainly refers to marriage, discussion of which is postponed till something becomes black or turns dark. Theiler's hardly fits thecontext, and Burkert's with the sense ‘when the grapes ripen’ is not convincing. A metaphorical sense for ‘grapes’ is preferable, e.g. or, better, , , ‘when youwill be old enough to marry’; but the phrase comes with a jolt in the absence of any preparation or immediate (...) follow-up: in the passages of Philodemus andHorace quoted as parallel by Ebert-Luppes the metaphor is not simply a singleword but is extended over two or three lines. (shrink)